Heart Failure: Molecules, Mechanisms and Therapeutic Targets
نویسندگان
چکیده
منابع مشابه
Therapeutic Targets in Heart Failure
From the *Heart Pittsburgh Schoo Cardiomyopathy C California; zCente School of Medici University, Atlanta Siemens; has receiv purposes; and has r The Pittsburgh F GlaxoSmithKline, Relypsa, Scios, St. as the Eliot Cord Ahmanson Found ew therapeutic targets, agents, and strategies are needed to prevent and treat heart failure (HF) after a decade of failed research efforts to improve long-term pat...
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Anemia ranges in prevalence from below 10% among patients with mild heart failure symptoms to over 40% for patients with advanced disease.1 Its prevalence is similar among patients who have systolic dysfunction and among patients who have heart failure with preserved systolic function.2,3 Anemia has been associated with older age, diabetes mellitus, chronic renal dysfunction, more advanced hear...
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Toll-like receptors (TLRs) have been identified as central innate immune receptors. They distinguish among different patterns of pathogens and rapidly activate an innate immune response. However, TLRs can also be stimulated by host-derived molecules. They are expressed in the cardiovascular system and could thus be a key link between cardiovascular diseases and the activation of the immune syst...
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Chronic heart failure (CHF) is a highly prevalent condition among the elderly and is associated with considerable morbidity, institutionalization and mortality. In its advanced stages, CHF is often accompanied by the loss of muscle mass and strength. Sarcopenia is a geriatric syndrome that has been actively studied in recent years due to its association with a wide range of adverse health outco...
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Metabolismo do ferro na insuficiência cardíaca: mecanismos e abordagens terapêuticas Anemia is frequent in heart failure (HF) patients, and is considered an independent factor for worse prognosis. However, it is not known whether anemia causes worsening of the disease course or is only a sign of the patient's cardiac and systemic impairment. The definition of anemia according to the World Healt...
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ژورنال
عنوان ژورنال: Circulation
سال: 2007
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.106.674127